In vitro high-throughput drug sensitivity screening with patient-derived primary cells as a guide for clinical practice in hepatocellular carcinoma—A retrospective evaluation

•Adjuvant chemotherapy is a useful postoperative treatment method for patients with hepatocellular carcinoma.•Accurate individualized treatment of tumor patients is a positive treatment.•The first generation of cells cultured from patients’ post-operative specimens for drug sensitivity can avoid the cell mutations caused by repeated culture.•High-throughput drug sensitivity screening can be a new method for determining drug sensitivity for hepatocellular carcinoma.