Gestational hypercalcemia: Prevalence and biochemical profile

Inez Schoenmakers,Shereen Baban,Isabelle Piec,Darrell Green,Christopher Washbourne,Jonathan Tang,William D. Fraser,Linnea Barebring,Hanna Augustin

The Journal of Steroid Biochemistry and Molecular Biology（2019）

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摘要

•Population prevalence of gestational hypercalcemia was 1.7 % in the third trimester.•Hyperparathyroidism and vitamin D toxicity were excluded as main causes.•No cases with profiles suggestive of mutations in the CYP24A1 gene were found.•Hypercalcemic women had a relatively high serum 1,25(OH)2D concentration despite an appropriately suppressed PTH.

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关键词

Pregnancy,Hypercalcemia,Vitamin D metabolites,Free 25 hydroxy vitamin D,Case-control study

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