Panel 3: Genomics, precision medicine and targeted therapies.

International Journal of Pediatric Otorhinolaryngology(2020)

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摘要
In the future otitis media prevention strategies may be augmented by mucosal immunization, combination vaccines targeting multiple pathogens, and modulation of the middle ear microbiome. Both treatment and vaccination may be tailored to an individual's otitis media phenotype as defined by molecular profiles obtained by using rapidly developing techniques in microbial and host genomics.
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关键词
Otitis media,Otitis-prone,Microbiome,Metagenomics,Genome-wide association study,Precision medicine
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