Extent of cortisol suppression at baseline predicts improvement in HPA axis function during antidepressant treatment.

Maike Scherf-Clavel,Catherina Wurst,Felix Nitschke,Saskia Stonawski,Carolin Burschka,Lisa Friess,Stefan Unterecker,Leif Hommers,Jürgen Deckert,Katharina Domschke,Andreas Menke

Psychoneuroendocrinology（2020）

引用 8|浏览32

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摘要

•A suppression index of cortisol before and after GR-stimulation was established.•A threshold predicted HPA axis reactivity during antidepressant therapy.•The threshold was replicated in an independent patient sample.

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关键词

Dexamethasone suppression test,Major depressive disorder,Precision treatment

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