Piperine alkaloid induces anticancer and apoptotic effects in cisplatin resistant ovarian carcinoma by inducing G2/M phase cell cycle arrest, caspase activation and inhibition of cell migration and PI3K/Akt/GSK3β signalling pathway.
Journal of B.U.ON. : official journal of the Balkan Union of Oncology（2019）
Abstract
These results suggest that Piperine exerts potent anticancer effects on ovarian cancer cells and may prove beneficial in the management of ovarian cancer.
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Key words
ovarian cancer,piperine,apoptosis,cell cycle arrest
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