Local assessment of WC1 + γδ T lymphocyte subset in the different types of lesions associated with bovine paratuberculosis.

Comparative Immunology, Microbiology and Infectious Diseases(2020)

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摘要
•WC1+ γδ T lymphocytes were present in the intestinal tissue of both healthy cows and those affected by paratuberculosis.•The number of WC1+ γδ T lymphocytes was higher in infected than in control cows.•WC1+ γδ T cells in lamina propria from infected animals significantly outnumbered those in control animals.•Focal lesions showed greater number WC1+ γδ T lymphocytes than diffuse paucibacillary and multibacillary forms.•In cows with focal lesions, WC1+ γδ T lymphocytes tended to be distributed at the periphery of granulomas.
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关键词
Bovine,Immunohistochemistry,Granuloma,Paratuberculosis,γδ T cell,WC1+
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