N-acetyl cysteine protects against chlorine-induced tissue damage in an ex vivo model.

Lina Ågren,Linda Elfsmark,Christine Akfur,Lars Hägglund,Barbro Ekstrand-Hammarström,Sofia Jonasson

Toxicology Letters（2020）

引用 8|浏览7

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摘要

•Exposure to Cl2 induced a concentration-dependent cytotoxicity and tissue damage•N-acetyl cysteine-treatment improved cell viability and reduced tissue damage•PCLS is a method that could be proposed for drug discovery after Cl2-exposure

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关键词

Precision-cut lung slices (PCLS),Chlorine,Lung-injury,N-acetyl cysteine,Treatment,Rat

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