Single Dose Of Doxycycline For The Prevention Of Tick-Borne Relapsing Fever

Yoav Binenbaum,Ronen Ben-Ami,Gad Baneth,Boaz Langford, Yoav Negev, Edwa Friedlander,David Shasha,Luba Tau,Yael Paran

CLINICAL INFECTIOUS DISEASES（2020）

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摘要

The current postexposure prophylaxis regimen for tick-borne relapsing fever (TBRF) consists of 5 days' doxycycline. In this observational study of 77 spelunkers at high risk for TBRF, a single dose of 100 mg doxycycline taken up to 72 hours after exposure to ticks was 100% effective in preventing the disease.

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