Outcomes in women with biopsy-confirmed cervical intraepithelial neoplasia grade 1 or normal cervix and related cofactors: A 15-year population-based cohort study from China.

•A 15-year population-based study to evaluate the natural history of biopsy-confirmed CIN1 or normal cervix in rural China.•CIN1 or normal women with positive hrHPV or cytologic HSIL+ could be immediately treated if surveillance is inaccessible.•Screening interval could be prolonged for CIN1 or normal women without hrHPV or cytology abnormalities.•Younger age of sexual debut is associated with a higher risk of acquiring new and repeated HPV infections.