Effects of donor–recipient combinational CYP3A5 genotypes on tacrolimus dosing in Chinese DDLT adult recipients

Jianyu Liu,Dexi Chen,Bo Yao,Ge Guan,Chao Liu,Xinmin Jin,Xin Wang,Peng Liu,Yandong Sun,Yunjin Zang

International Immunopharmacology（2020）

Cited 5|Views42

No score

Abstract

•Genetic factors contributed the most to Tac C/D variability.•The effect of the recipient’s genetics was correlated only in the first three months.•The role of the donor CYP3A5 genotype was observed throughout the timeline.•The donor’s liver CYP3A5 genotype contributed increasingly after transplantation.

Translated text

Key words

Liver transplant,Tacrolimus,Recipient,Donor,CYP3A5 genotype

AI Read Science

Must-Reading Tree

Example

Generate MRT to find the research sequence of this paper

Chat Paper

Summary is being generated by the instructions you defined