Baicalin Attenuates Mycoplasma gallisepticum -Induced Inflammation via Inhibition of the TLR2-NF-κB Pathway in Chicken and DF-1 Cells.

The results showed that baicalin can interfere with inflammatory injury by suppressing the release of inflammatory cytokines IL-1β and TNF-α during infection both in vivo and in vitro. Meanwhile, baicalin suppressed TLR2-NFκB signaling pathway by inhibiting the phosphorylation of p65 and IκB, thereby affecting the expression of inflammatory factors. The results suggested that baicalin acts as a potential anti-inflammatory agent against infection in chicken and DF-1 cells.