Genetic risk for dengue hemorrhagic fever and dengue fever in multiple ancestries. Guillaume Pare , Binod Neupane , Sasha Eskandarian , Eva Harris , Scott Halstead , Lionel Gresh , Guillermina Kuan , Angel Balmaseda , Luis Villar , Elsa Rojas , Jorge E Osorio , Dang Duc Anh , Aruna Dharshan De Silva , Sunil Premawansa , Gayani Premawansa , Ananda Wijewickrama , Ivette Lorenzana , Leda Parham , Cynthia Rodriguez , Ildefonso Fernandez-Salas , Rosa Sanchez-Casas , Esteban E Diaz-Gonzalez , Khin Saw Aye , Win Lai May , Min Thein , Filemon Bucardo , Yaoska Reyes , Patricia Blandon , Kenji Hirayama , Lan Weiss , Pardeep Singh , Jennifer Newton , Mark Loeb EBioMedicine(2020)
摘要
There is a strong genetic effect that predisposes to risk of DHF/DSS and DF. The genetic risk for DHF/DSS is higher than that for DF when compared to controls, and this effect persists across multiple ancestries.
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Dengue, Genetics, Risk, GWAS, Ancestry
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