Apple polysaccharide protects ICR mice against colitis associated colorectal cancer through the regulation of microbial dysbiosis.

Carbohydrate Polymers(2020)

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摘要
•Apple polysaccharide (AP) prevented from colitis associated colorectal cancer.•AP restored AOM/DSS-caused intestinal microbiota disorder.•AP inhibited the activation of classical Wnt pathway in colon tissues.•AP decreased the quantity of Fusobacterium directly and/or indirectly.
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关键词
AOM,Bde,Bte,CACC,DSS,Fus,ICR,Lac,LPS,AP
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