Object and food novelty induce distinct patterns of c-fos immunoreactivity in amygdala and striatum in domestic male chicks (Gallus gallus domesticus).

•The neural bases of neophobia in birds were investigated by immunohistochemistry.•C-fos expression in the amygdala depends on the type of novelty.•C-fos expression in the striatum is similar following object or food novelty.•The motivational and limbic systems are involved in neophobia in chicks.