Pulmonary carcinoid tumor: a single institution experience

Introduction: Pulmonary carcionoid tumors are rare tumors that account for less than 1% of all lung cancers. They are classified as typical carcinoid (TC) or atypical carcinoid (AC), based on the mitotic index and/or presence of necrosis. Aim: The purpose of this retrospective study was to describe pathologic parametres, clinical behaviour and outcomes of patients treated for pulmonary carcinoid tumors Methods: We have retrospectively reviewed the hospital records of all patients with diagnosis of pulmonary carcinoid, treated from 2009. to 2015. Data collected included demographics, pathology (tumor size, lymph node status, metastases-TNM status ), treatment, recurrence of tumor and survival. Results: There were 64 cases of pulmonary CT: 48 typical ( 75 %) and 16 atypical ( 25%). All patients underwent surgery, 3 recived concurrent adjuvant chemoradiation therapy (1 patient with TC and 2 with AC). 1 patient with TC and 1 patient with AC were treated only with adjuvant chemotherapy. Recurrent tumors developed in 3 patients with TC and 5 with AC. Ki 67 % expression was stronger in AC (median 11,75%) than TC (median 3,75%). Survival rate of patients with TC was higher (median 91,2 months) than survival rate of patients with TC (median 65,9 months). Conclusion: Survival of carcinoid tumors was favorable. Survival distribution in this analysis was statistically different for the age higher than 60 years, atypical histological type of carcinoid, tumor size greater than 4 cm and Ki-67% expression higher than 5%.