Anti-inflammatory effect of Rhodiola crenulata extracts through the down-regulation of MyD88 dependent pathway and induction of autophagy

Jae-Woong Lee,Yon-Suk Kim,Xin Dong,Jin-Su Park,Woen-Bin Shin, Su-Jin Kim,Eun-Ae Go,Pyo-Jam Park

Journal of Functional Foods（2020）

引用 8|浏览23

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摘要

•Rhodiola crenulata water extract (RCW) has an anti-inflammatory effect.•RCW reduces pro-inflammatory mediators such as NO, IL-6 and IL-1β.•RCW regulates MAPK and NF-ĸB signaling of MyD88-dependent pathway.•RCW induces HO-1 dependent autophagy expression.

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关键词

Rhodiola crenulata,Anti-inflammatory effect,RAW264.7 cells,Peritoneal macrophages,Autophagy

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