Recommendations for measuring whisker movements and locomotion in mice with sensory, motor and cognitive deficits

Ugne Simanaviciute, Jewel Ahmed,Richard E Brown,Natalie Connor-Robson,Tracy D. Farr,Emre Fertan, Nikki Gambles,Huw Garland,A. Jennifer Morton,Jochen F. Staiger,Elizabeth A. Skillings,Rebecca C. Trueman,Richard Wade-Martins,Nigel I. Wood,Aimee A. Wong,Robyn A. Grant

Journal of Neuroscience Methods（2020）

引用 8|浏览18

暂无评分

摘要

•Mice move their whiskers during tactile exploration.•We measure whisker movements and locomotion in 9 mouse strains.•Genotype, background strain, sex and source breeder affected whisker movements.•8 of the 9 models showed differences in whisker movements, compared to controls.•We recommend a standardized protocol to measure whisker movements.

查看译文

关键词

Rodent,Sensorimotor,Barrel cortex,Animal behaviour,Neurodegeneration,Disease models,Transgenic,Mouse models

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要