Blood Brain Barrier: A Tissue Engineered Microfluidic Chip

Sikkandhar Musafargani,Sachin Mishra,Miklós Gulyás,P. Mahalakshmi,Govindaraju Archunan,Parasuraman Padmanabhan,Balázs Gulyás

Journal of Neuroscience Methods（2020）

引用 14|浏览8

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摘要

•There is an ongoing interest in designing BBB models to boost the field of neurotherapeutics.•Microfluidic BBB-on-a-Chip possess engineered physiological microenvironment for real time monitoring of barrier properties.•Various approaches of modelling microfluidic BBBs with limitations of existing models and technology is reviewed.

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关键词

BBB-on-a-Chip,Blood-brain barrier,Microfluidics,Shear stress,Permeability

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