In vivo cascade catalysis of aromatic amino acids to the respective mandelic acids using recombinant E. coli cells expressing hydroxymandelate synthase (HMS) from Amycolatopsis mediterranei

•Applying hydroxymandelate synthase from Amycolatopsis mediterranei in Escherichia coli BL21(DE3).•Establishing a whole cell biotransformation process for the production of mandelic acid and its derivatives from various phenylalanines.