The centrality of sense of self in psychological flexibility processes: What the neurobiological and psychological correlates of psychedelics suggest

•The psychological flexibility model can guide therapeutic use of psychedelics•The processes of change engaged by psychedelics overlap with that model•Changes in time, place, and person are central to the impact of psychedelics•These data fit with a hierarchical deictic approach to the perspective-taking self•A perspective-taking self may play a more central role in psychological flexibility