Primary cardiac neoplasms: Coexistence of papillary fibroelastomas of the tricuspid valve and myxoma of the mitral valve

Both cardiac myxomas and papillary fibroelastomas are primary benign cardiac tumors, but it is very rare for tumors with different histologies to occur in different valves of the same heart. A 5-month-old infant underwent resection of a mitral valve mass + mitral valvuloplasty at our hospital. The tricuspid valve mass was still small, and no tricuspid regurgitation was observed; therefore, the tricuspid valve mass was not treated. The postoperative pathology showed that the mitral valve mass was a myxoma. The patient presented to our hospital for a follow-up examination two years later, and color Doppler ultrasound showed enlargement of the mitral valve and tricuspid valve mass as well as aggravation of regurgitation of the two valves. We performed resection of the mitral valve mass with mechanical valve replacement + resection of the tricuspid valve mass together with tricuspid valvuloplasty for this child. Postoperative pathology showed myxoid degeneration of the mitral valve and papillary fibroelastoma/tumor-like hyperplasia of the tricuspid valve. One month after the patient underwent surgery, the follow-up examination was satisfactory. Keywords: Cardiac myxoma, Cardiac papillary fibroelastoma, Myxomatous degeneration, Heterogeneous tumor