Adversity exposure during sensitive periods predicts accelerated epigenetic aging in children (vol 113, 104484, 2020)

Psychoneuroendocrinology(2020)

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摘要
•Exposure to adversity was associated with accelerated epigenetic aging in childhood.•Associations were observed when using the Hannum but not Horvath epigenetic clock.•Effects were driven by exposure during early and middle childhood sensitive periods.•Adversity differentially affected epigenetic age acceleration in boys and girls.
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关键词
Sensitive periods,Epigenetic clock,Aging,ALSPAC,Adversity
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