Patient-Reported Neuropsychiatric Outcomes Of Long-Term Survivors After Chimeric Antigen Receptor (Car)-T Cell Therapy

Merav Bar,Julia Ruark,Erin Mullane,Nancy Cleary,Ana Cordeiro,Evandro D. Bezerra,Jenna M. Voutsinas,Bronwen E. Shaw,Qian Vicky Wu,Kathryn E Flynn,Stephanie J. Lee,Cameron J. Turtle,David G. Maloney,Jesse Fann

BLOOD（2019）

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摘要

CD19-targeted chimeric antigen receptor (CAR)-T cell therapy is a novel treatment with promising results for patients with relapsed/refractory lymphoid malignancies. CAR-T cell therapy has known early toxicities of cytokine release syndrome (CRS) and neurotoxicity, but little is known about long-term neuropsychiatric adverse effects.

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关键词

chimeric antigen receptor,therapy,survivors,patient-reported,long-term

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