The association between vitamin D receptor gene polymorphisms and the risk of nephrolithiasis: A meta-analysis

Meta Gene(2020)

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摘要
•There is no association between nephrolithiasis and both Apa-I and BsmI gene polymorphisms.•Increased risk of nephrolithiasis is associated with FF genotype of Fok-I.•T allele and TT genotype of Taq-I are associated with reduced risk of nephrolithiasis. While, increased risk of nephrolithiasis is associated with t allele and tt genotype of Taq-I.•The association between Fok-I and the risk of nephrolithiasis is observed in Asian population. While, the association between Taq-I and the risk of nephrolithiasis is found in Caucasian population.•Taq-I has more powerful association with the risk of nephrolithiasis than Fok-I.
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关键词
Nephrolithiasis,Vitamin D receptor,Gene polymorphisms
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