Nerve Regeneration: Repairing Transected Peripheral Nerve Using a Biomimetic Nerve Guidance Conduit Containing Intraluminal Sponge Fillers (Adv. Healthcare Mater. 21/2019)

Repair of segmental nerve defects remains a troublesome issue in the clinic. In article number 1900913 by Xinyu Wang and co-workers, an innovative nerve guide conduit (ISF-NGC) is constructed by combining a nanofibrous external conduit and intraluminal sponge fillers. The ISF-NGC provides extracellular matrix (ECM)-like architecture for axonal regrowth and effectively facilitates nerve regeneration.