Data Presenting The Synthesis Of Three Novel Stimuli Responsive Hyperbranched Polymers Synthesised Via Raft Polymerisation And The Bio Conjugation Of Folic Acid

DATA IN BRIEF(2020)

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摘要
The data presented in this manuscript presents the characterisation spectra of three hyperbranched polymers as discussed in the paper "Folic Acid and Rhodamine Labelled pH Responsive Hyperbranched Polymers: synthesis, characterisation and cell uptake studies" [1]. Characterisation of polymers was performed via H-1 Nuclear Magnetic Resonance (H-1 NMR) and Size Exclusion Chromatography (SEC). pH responsive characteristics were observed via Dynamic Light Scattering (DLS). The data for characterisation of folate conjugated hyperbranched polymer is presented as 1H NMR, Ultra Violet Visible (UV-VIS) spectra and DLS measurements. Further data is presented detailing the experiments for the synthesis of monomers 2-propyl acrylic acid (PAA) and disulfide diacrylate (DSDA), with the full synthesis of folic acid-poly ethylene glycol) (PEG) linker, rhodamine B ethylenediamine linker and bioconjugation reactions also detailed. (C) 2019 The Author(s). Published by Elsevier Inc.
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关键词
Hyperbranched polymers, pH responsive, RAFT polymerisation, Targeted delivery
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