Protein adduct binding properties of tabun-subtype nerve agents after exposure in vitro and in vivo.

Feiyan Fu,Haibo Liu,Runli Gao,Pengcheng Zhao,Xiaogang Lu,Ruihua Zhang,Liangliang Wang,Hongmei Wang,Chengxin Pei

Toxicology Letters（2020）

引用 12|浏览8

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摘要

•The binding properties of tabun-subtype nerve agents were investigated.•The binding mechanism with selectivity to lysine residues were studied.•K525 and K414 can serve as the primary biomarkers for traceability of GAs exposure in humans.

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关键词

Nerve agents,Tabun,Albumin,Q-Orbitrap,Lysine adducts

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