Chordoma of the sacrum of an adult naked mole-rat.

Jordan E Cole,James C Steeil, Steven J Sarro,Kenton L Kerns,Andrew Cartoceti

JOURNAL OF VETERINARY DIAGNOSTIC INVESTIGATION(2020)

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摘要
The naked mole-rat (NMR; Heterocephalus glaber)-a small, eusocial, subterranean rodent native to East Africa-is distinguished by its capability to live long and resist changes associated with the aging process. Notably, a growing amount of research has been dedicated to NMRs' multifactorial capacity to resist cancer. Since 2016, however, zoos have begun to document various neoplasms in a handful of individuals. We present herein radiographic, gross anatomic, and histopathologic features of a case of a sacral chordoma in a geriatric female. Chordomas originate in notochordal remnants. These spinal tumors are most commonly seen in ferrets; chordomas are rare in humans, can be difficult to treat, and need wide surgical margins.
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关键词
chordoma,Heterocephalus glaber,naked mole-rats,neoplasia
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