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Andrographolide derivative AL-1 reduces intestinal permeability in dextran sulfate sodium (DSS)-induced mice colitis model.

Nan Jiang,Yuke Wei,Yun Cen,Luchen Shan,Zaijun Zhang,Pei Yu,Yuqiang Wang,Lipeng Xu

Life Sciences（2020）

Cited 14|Views21
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Abstract
AL-1 could prevent the increase in the DSS-induced intestinal permeability. These data indicated that AL-1 could be a promising agent for UC treatment.
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DSS,UC,5-ASA,TJs,MUC-2,JAM-A,ZO-1,MLCK,MLC2,Andro,AL-1,LA,TNBS,DAI,H&E staining,PAS staining,DAO,PVDF,SDS-PAGE
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