Restoring strategy of ethanolic extract of Moringa oleifera leaves against Tilmicosin-induced cardiac injury in rats: Targeting cell apoptosis-mediated pathways.

•Tilmicosin (Til) induces a deleterious impact in the rat’s heart tissue.•Moringa oleifera ethanolic extract (MO) protects against ROS mediated-oxidative injury by enhancing the antioxidant system.•MO diminishes apoptosis via modulation of the expression of apoptosis pathway encoding genes.•MO administration restores the morphological alterations induced by Til in the rat’s heart tissue.•MO is a promising cardioprotective agent against Til-induced cardiac injury.