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Single-Molecule Translocation Conformational Sensing of Multi-Arm DNA Concatemers Using Glass Capillary Nanopore.

Ya Zhou,Ruiping Wu, Dandan Wang,Ping Hu,Yongdong Jin

ACS sensors（2019）

Cited 10|Views5
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Abstract
Glass capillary-based nanopore is exploited for single-molecule conformational sensing of multi-arm DNA concatemers during translocation. Both translocation frequency and orientation preference were found related with the number of arms of the DNA concatemers.
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Key words
glass nanopore,DNA concatemers,single-molecule translocation,ionic current,conformational sensing
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