The Impact of Proline Isomerization on Antigen Binding and the Analytical Profile of a Trispecific Anti-Hiv Antibody

Alessandro Masiero,Lechat Nelly, Gentric Marianne, Sourrouille Christophe, Laville Florian, Crepin Ronan, Borel Claire, Ziegler Cornelia, Bisch Gregoire, Leclerc Eric, Laurent Ludovic, Brault Dominique, Alexandre Sylvie,Gagnaire Marie,Duffieux Francis,Soubrier Fabienne,Capdevila Cecile,Arnould Isabelle,Dumas Jacques, Dabin Jerome,Genet Bruno,Radosevic Katarina,Menet Jean-Michel,Prades Catherine

mAbs（2019）

Cited 14|Views28

Key words

Proline isomerization,antibody conformers,chemical equilibrium,developability

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