Probing excited conformational states of nucleic acids by nitrogen CEST NMR spectroscopy.

Journal of Magnetic Resonance（2020）

引用 15|浏览9

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摘要

•Protonated G-N1 and U-N3 15N CEST used to probe chemical exchange in RNA.•Non-protonated G-N7 and A-N1/N3/N7 15N CEST used to probe chemical exchange in RNA.•15N CEST complements 13C CEST for more comprehensive mapping of RNA dynamics.

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关键词

RNA dynamics,Chemical exchange,Riboswitch,Ligand binding

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