Efficacy and safety of haloperidol for delirium prevention in adult patients: An updated meta-analysis with trial sequential analysis of randomized controlled trials

Zhen Chen,Rui Chen,Donghua Zheng,Yongpeng Su, Shuchao Wen, Huocheng Guo, Zhigang Ye,Yingxin Deng,Genglong Liu,Liuer Zuo,Xuxia Wei,Yunqi Hou

Journal of Clinical Anesthesia（2020）

引用 13|浏览9

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摘要

•The use of prophylactic haloperidol compared with placebo had no beneficial impacts on incidence of delirium.•It appeared to have a positive effect on duration of delirium, while with a significant heterogeneity.•These findings do not support the routine usage of haloperidol for delirium prevention.

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关键词

Haloperidol,Delirium,Prevention,Meta-analysis,Trial sequential analysis

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