Chromatic serial multiphoton microscopy for high-content multiscale analysis of large brain volumes

Lamiae Abdeladim,Katherine Matho,Solène Clavreul,Pierre Mahou,Jean-Marc Sintes,Xavier Solinas,Ignacio Arganda-Carreras,Anatole Chessel,Steve Turney,Jeff W. Lichtman, Alexis-P. Bemelmans,Karine Loulier,Willy Supatto,Jean Livet,Emmanuel Beaurepaire

Brain（2019）

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摘要

Large-scale microscopy techniques are transforming brain imaging but lack efficient multi-contrast modalities. Our work combines two-photon wavelength-mixing and serial tomography microscopy to overcome this limitation, and demonstrates the potential of this approach in various contexts.

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关键词

chromatic serial multiphoton microscopy,large brain volumes,multiscale analysis,high-content

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