Halophilic bacteria as a potential management for autism
ROMANIAN BIOTECHNOLOGICAL LETTERS(2019)
Abstract
Autism spectrum disorders (ASD) are serious neurodevelopmental disorders with poorly understood etiology. Autism has more than one clear cause, which connect to each other leading by multiple connected steps to autism development. Because of the increased incidence of autism pathogenesis in recent years, an increased need to effective treatment has been noticed. The fact that autism has been reported as being a result of oxidative stress and gut microbiome imbalances has motivated researchers to treat autism by treating whether one or the other of these two main causes. Nevertheless, the treatment of just one of these factors has had a lot of limitations. Therefore, we propose in this review a natural treatment by using Halophilic bacterial biomolecules with both antagonistic and antioxidant effects, which could target both gut microbiome and oxidative stress disturbances, increasing then the chance of treating autism pathogenesis at an earlier state.
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Key words
Autism spectrum disorders,Oxidative stress,Gut microbiota,Halophilic microorganisms,Natural biomolecules
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