A fructan from Anemarrhena asphodeloides Bunge showing neuroprotective and immunoregulatory effects

Shaojie Zhang,Qi Zhang,Lijun An,Jiaojiao Zhang,Zhengguo Li,Jie Zhang,Yuhao Li,Muhetaer Tuerhong,Yasushi Ohizumi,Jin Jin,Jing Xu,Yuanqiang Guo

Carbohydrate Polymers（2020）

Cited 51|Views40

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Abstract

•A novel fructan, AAP70-1, was isolated from A. asphodeloides for the first time.•The structure and morphology of AAP70-1 were characterized for the first time.•AAP70-1 exhibited significant neuroprotective activity in an SH-SY5Y cells injury model.•AAP70-1 significant enhanced the immunoregulatory activity of RAW264.7 cells.

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Key words

D-Glucose (PubChem CID: 5793),Trifluoroacetic acid (PubChem CID: 6422),Chloroform (PubChem CID: 6212),Methyl iodide (PubChem CID: 6328),Cobalt dichloride (PubChem CID: 24288),Tocopherol (PubChem CID: 14986),Penicillin G (PubChem CID: 5904),Streptomycin (PubChem CID: 19649),Dimethyl sulfoxide (PubChem CID: 679),Neutral red (PubChem CID: 11105)

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