Cover Feature: N‐Ethynylation of Anilides Decreases the Double‐Bond Character of Amide Bond while Retaining trans‐Conformation and Planarity (Chem. Eur. J. 43/2019)

N-Alkynylated anilides can retain a trans conformation as secondary amides, in contrast with N-alkyl and vinyl derivatives, which exist in cis conformation. From a structural perspective, the N-alkynylated amide has a less C=N double bond character than those of N-alkyl derivatives and showed lability toward hydrolysis. This amide activation strategy is apparent from the planarity of its amide bonds, because the majority of known activation methods destroy amide planarity. More information can be found in the Full Paper by R. Yamasaki, I. Okamoto et al. on page 10118.