Clinical Efficacy Of Transforaminal Percutaneous Endoscopic Lumbar Discectomy Combined With Ozone Therapy For The Treatment Of Lumbar Disc Herniation: Comparison With Fenestration Discectomy. A Prospective Study

The aim of this prospective study was to investigate the clinical efficacy of the transforaminal percutaneous endoscopic lumbar discectomy (PELD), combined with ozone in the treatment of lumbar disc herniation, and to compare its short-term efficacy with fenestration. The study included 109 adult patients admitted to our hospital from January 2015 to December 2016 that met the inclusion criteria. All patients were randomly divided into two groups: the combination group and the fenestration group. The visual analogue scale (VAS) was used to measure postoperative pain of the surgical wound and waist and leg. The JOA score was used to measure recovery status, and the Oswestry disability index (ODI) was used to determine lumbar dysfunction. The operation time and hospitalization time in the combined group were significantly shortened, and the average blood loss and the average amount of intervertebral disc resection were also significantly lower than those in the fenestration group. At all-time points, the VAS score of postoperative pain in the combined group was significantly lower than that in the control group. VAS and ODI scores were significantly decreased and JOA scores were significantly higher in the combined group. The treatment rate in the combined group was significantly higher than that in the open window group. However, there was no a significant difference in the incidence of complications between the two groups. PELD combined with ozone therapy can significantly improve the therapeutic effects and shorten the recovery time of patients with lumbar disc herniation, but does not affect the incidence of postoperative complications.