Imetelstat inhibits growth of megakaryocyte colony-forming units from patients with essential thrombocythemia

Gabriela M Baerlocher,Monika Haubitz,Thomas R Braschler,Claudio Brunold,Bart Burington,Elisabeth Oppliger Leibundgut,Ning Go

Blood Advances（2019）

引用 7|浏览14

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摘要

Key Points Clinically relevant imetelstat concentrations significantly inhibit CFU-MEG formation from MNCs of ET patients and reduce hTERT expression. However, similar concentrations of imetelstat do not inhibit cytokine-induced CFU-MEG from MNCs of healthy donors.

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关键词

essential thrombocythemia,colony-forming

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