Simplified Non-Thermal Tissue Ablation With A Single Insertion Device Enabled By Bipolar High-Frequency Pulses.

Matthew R DeWitt, Ian McKillop,Rafael V Davalos, Michael Sano,Eduardo Lattouche, Jacob D Kaufman,Christopher C Fesmire,Jacob Swet,Russel Kirks, Eric Baker,Dionisios Vrochides,David Iannitti

IEEE Transactions on Biomedical Engineering（2020）

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摘要

Objective: To demonstrate the feasibility of a single electrode and grounding pad approach for delivering high frequency irreversible electroporation treatments (H-FIRE) in in-vivo hepatic tissue. Methods: Ablations were created in porcine liver under surgical anesthesia by adminstereing high frequency bursts of 0.5–5.0 μs pulses with amplitudes between 1.1–1.7 kV in the absence of cardiac synchro...

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关键词

Electrodes,Liver,Animals,Voltage measurement,Grounding,Electric fields,Tumors

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