Fgf21 Knockout Mice Generated Using CRISPR/Cas9 Reveal Genetic Alterations That May Affect Hair Growth.

Xu Liu,Ping Zhang,Xiaofeng Zhang,Xing Li,Yu Bai,Yue Ao,Bayar Hexig,Xudong Guo,Dongjun Liu

Gene（2020）

引用 12|浏览30

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摘要

•Fgf21 knockout mice were constructed by using CRISPR/Cas9 system.•Fgf21-/- could affect murine hair follicles’ growth speed and number of hair shafts.•The roles of Fgf21 in hair growth associated with Pi3k/Akt and Mapk/Erk signalings.

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关键词

AKT,RT-qRCR,GAPDH,EDTA,PBS,ERK,PI3K,MAPK,Fgf21,PCR

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