Kaempferol protects retinal ganglion ceils from high-glucose-induced injury by regulating vasohibin-1.

Lu Zhao, Junbo Sun, Suqin Shi,Xiao Qin, Keke Zhang,Jiangyan Xu

Neuroscience Letters(2020)

Cited 17|Views13
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Abstract
•Kaempferol maintains cell viability and membrane integrity in RGC cells injured by high glucose•Kaempferol reduces apoptosis and caspase-3 activity in RGC cells exposed to high glucose•Kaempferol inhibits ROS in RGC exposed to high glucose•Kaempferol protected RGC cells by modulating ERK activation and VASH1 expression
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Key words
Kaempferol,Diabetic retinopathy,Retinal ganglion cells,High glucose,Extracellular signal regulated kinase 1/2,Vasohibin-1
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