Sema3A inhibits axonal regeneration of retinal ganglion cells via ROCK2.
Brain Research(2020)
Abstract
•Sema3A may negatively regulate axonal outgrowth in RGCs.•The suppressive role of Sema3A can be attenuated by blocking ROCK2.•Sema3A promotes phosphorylation of MLC2 during the optic nerve regeneration.
MoreTranslated text
Key words
Semaphorin3a (Sema3A),Retinal ganglion cells (RGC, RGCs),Rho-associated protein kinase 2 (ROCK2),Axonal regeneration
AI Read Science
Must-Reading Tree
Example
![](https://originalfileserver.aminer.cn/sys/aminer/pubs/mrt_preview.jpeg)
Generate MRT to find the research sequence of this paper
Chat Paper
Summary is being generated by the instructions you defined