Risk factors for depression in adults: NR3C1 DNA methylation and lifestyle association.

Aline Ribeiro Borçoi,Suzanny Oliveira Mendes,Joaquim Gasparini Dos Santos,Mayara Mota de Oliveira,Ivana Alece Arantes Moreno,Flávia Vitorino Freitas,Júlia Assis Pinheiro,Juliana Krüger Arpini,Ester Ribeiro Cunha,Anderson Barros Archanjo,Aricia Leone Evangelista Monteiro de Assis,Bruna Pereira Sorroche,Lídia Maria Rebolho Batista Arantes,Elizeu Borloti,Adriana Madeira Álvares-da-Silva

Journal of Psychiatric Research（2020）

引用 15|浏览18

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摘要

•This study analyzes the relationship between depression, epigenetics changes in HPA axis and lifestyle.•Higher NR3C1 DNA methylation levels and low cortisol levels were associated with depression.•Tobacco use, self-perceived stress, leisure activity and suicidal ideation also predicted risk factors for depression.

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