LncRNA TDRG1 promotes the aggressiveness of gastric carcinoma through regulating miR-873-5p/HDGF axis.

•LncRNAs TDRG1 is upregulated in clinical gastric carcinoma (GC).•TDRG1 promotes GC cell growth and metastatic-related traits in vitro and in vivo.•TDRG1 interacts with miR-873-5p and positively modulates the expression of HDGF.•TDRG1 regulates the progression of GC through regulating miR-873-5p/HDGF pathway.