Alemtuzumab-induced lung injury in multiple sclerosis: Learning from adversity in three patients.

Assunta Bianco,Pier-Valerio Mari,Anna Rita Larici,Matteo Lucchini,Viviana Nociti,Francesco Antonio Losavio,Chiara De Fino,Giuseppe Cicchetti,Daniele Coraci,Luca Richeldi,Massimiliano Mirabella

Multiple Sclerosis and Related Disorders（2020）

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摘要

•We report three cases of severe lung injury in MS patients treated with alemtuzumab.•Lung injury was heterogeneous in terms of clinic characteristics, HRCT pattern and onset timing.•All cases were reversible after steroid therapy, but re-treatment is challenging.

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关键词

Pulmonary toxicity,Personalized medicine,Interstitial pneumonitis,Acute respiratory distress syndrome,Diffuse alveolar haemorrhage

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