Protective efficacy of vaccines of the Korea national antigen bank against the homologous H5Nx clade 2.3.2.1 and clade 2.3.4.4 highly pathogenic avian influenza viruses.
Vaccine（2020）
Abstract
•Five inactivated vaccines were generated for Korean AI national antigenic bank for HPAI emergency preparedness.•Vaccines provide good protection in SPF chickens against homologous HPAI virus.•Vaccines produce high immunity from a single dose with sufficient antigen mass.•Vaccines induce long-lasting antibody responses to prevent mortality and virus shedding.
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Key words
Highly pathogenic avian influenza,Inactivation,Antigen bank,Chicken,Vaccine
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