Design and synthesis of biaryloxazolidinone derivatives containing amide or acrylamide moiety as novel antibacterial agents against Gram-positive bacteria.

Sicong Xu,Jia Jiang,Yinliang Qi,Xiudong Ding,Yachuang Wu,Hong Lei,Yanfang Zhao

Bioorganic & Medicinal Chemistry Letters（2019）

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摘要

A series of novel biaryloxazolidinone derivatives containing amide or acrylamide structure were designed, synthesized and evaluated for their antibacterial activity.

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关键词

Biaryloxazolidinone,Antibacterial activity,Gram-positive bacteria

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