OC29.05: A comparison of the pregnancy outcomes between women with a didelphus uterus and a unicornuate uterus after in vitro fertilisation‐embryo transfer

To investigate the pregnancy outcomes between women with a didelphus uterus and those with a unicornuate uterus after in vitro fertilisation-embryo transfer (IVF-ET). This was a retrospective analysis of 50 infertile women with a didelphus uterus and 280 cases with a unicornuate uterus from January 2004 to December 2017 at our reproductive centre. All women conceived a singleton pregnancy after IVF-ET at our reproductive centre. The diagnoses of uterine malformations were based on American Fertility Society (AFS) classification system. The outcome measures included pregnancy and obstetric outcomes, which were compared between the didelphus uterine group and the unicornuate uterine group. The didelphus uterine group and the unicornuate uterine group were statistically similar regarding maternal age ( 30.4 ± 4.7 vs. 29.9 ± 4.5 years; P = 0.505), infertility type (P = 0.462), cause of infertility (P = 0.070) and insemination methods (P = 0.261). The didelphus uterine group and the unicornuate uterine group had similar rates of miscarriage (18.0 vs. 20.7%; P = 0.660), ectopic pregnancy (0 vs. 1.1%; P = 1.000), preterm delivery (16.0 vs. 13.6%; P = 0.648), term delivery (66.0 vs. 64.6%; P = 0.853), very preterm birth (2.4 vs. 2.7%; P = 0.913), low live birth weight (12.2 vs. 11.6%; P = 0.918), very low live birth weight (2.4 vs. 0.5%; P = 0.295), Caesarean section (85.4% vs. 84.0%; P = 0.828), live birth (82.0 vs. 76.8%; P = 0.415) and perinatal mortality (0 vs. 1.8%; P = 1.000); additionally, the gestational age at delivery (38.2 ± 2.1 vs. 37.9 ± 2.7 weeks; P = 0.465) and the live birth weight (3026 ± 573 vs. 3072 ± 518 g; P = 0.608) had no significant differences between these two groups. For singleton pregnancy conceived via IVF-ET, women with a didelphus uterus and those with a unicornuate uterus had similar pregnancy and obstetric outcomes.